Ammonia → HCID 86641607, 화합물

HRID 1685180노트

반응식

[Cl:1][C:2]1[C:7]([NH:8][CH3:9])=[C:6](Cl)[N:5]=[CH:4][N:3]=1.[NH3:11]>>[Cl:1][C:2]1[N:3]=[CH:4][N:5]=[C:6]([NH2:11])[C:7]=1[NH:8][CH3:9]

참가 물질

반응물 2

HCID 222Ammonia

HCID 2502744,6-Dichloro-N-methylpyrimidin-5-amine

생성물 1

HCID 86641607HCID 86641607, 화합물수율 76.78%

실험 절차

Combine 4,6-dichloro-N-methylpyrimidin-5-amine (0.6 g; 0.0034 mol), and liquid ammonia (6 mL) and stir at 80° C. for 4 h. Extract with EA and evaporate to give the title compound (0.41 g; 76.78%).

후처리

extractionExtract with EA
customevaporate

출처 및 근거

ORD 기록: ord-68c3b315e27748538c175f40828dfc25
출처 데이터셋: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08148387B2

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