2-Chloro-6-methylphenol → 3-Chloro-4-hydroxy-5-methylbenzonitrile

HRID 1685697노트

반응식

HRID 1685697 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[OH:9].C(C1C=C(C=C(C)C=1O)[C:15]#[N:16])C>>[Cl:1][C:2]1[CH:7]=[C:6]([CH:5]=[C:4]([CH3:8])[C:3]=1[OH:9])[C:15]#[N:16]

참가 물질

3

반응물 2

HCID 68982-Chloro-6-methylphenolHCID 597599503-Ethyl-4-hydroxy-5-methylbenzonitrile

생성물 1

HCID 190383483-Chloro-4-hydroxy-5-methylbenzonitrile

실험 절차

The title compound is prepared from commercially available 2-chloro-6-methyl-phenol in analogy to literature procedures (see 3-ethyl-4-hydroxy-5-methyl-benzonitrile); LC-MS: tR=0.85 min. 1H NMR (CDCl3): δ 2.33 (s, 3H), 6.10 (s, 1H), 7.38 (s, 1H), 7.53 (d, J=1.8 Hz, 1H).

출처 및 근거

ORD 기록
ord-cca601a6503b49ebaba4bd2203b2e650
출처 데이터셋
uspto-grants-2012_04
특허 번호
US08148410B2

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