Dihydro-2H-thiopyran-3(4H)-one → tert-Butyl 2-[4-(3-oxothian-2-ylidenemethyl)phenyl]propionate

반응식

[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([CH:9]([CH3:17])[C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])=[CH:5][CH:4]=1)=O.[O:18]=[C:19]1[CH2:24][CH2:23][CH2:22][S:21][CH2:20]1>>[O:18]=[C:19]1[CH2:24][CH2:23][CH2:22][S:21][C:20]1=[CH:1][C:3]1[CH:8]=[CH:7][C:6]([CH:9]([CH3:17])[C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])=[CH:5][CH:4]=1

참가 물질

반응물 2

HCID 140474Dihydro-2H-thiopyran-3(4H)-one

HCID 86639388Tert-butyl 2-(4-formylphenyl)propionate

생성물 1

HCID 86639389tert-Butyl 2-[4-(3-oxothian-2-ylidenemethyl)phenyl]propionate수율 30%

실험 절차

By using tert-butyl 2-(4-formylphenyl)propionate (500 mg) and 3-oxothiane (500 mg), the title compound (210 mg, 30%) was obtained in the same manner as that of Example 1.

출처 및 근거

ORD 기록: ord-7eed7bd441db403c81cc20d9a2b1dd00
출처 데이터셋: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08148421B2

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