Benzyl acetone → 4-[2-(4-Phenylbutan-2-ylidene)hydrazinyl]pyridin-2(1H)-one

HRID 1686021노트

반응식

HRID 1686021 반응식
[NH:1]([C:3]1[CH:8]=[CH:7][NH:6][C:5](=[O:9])[CH:4]=1)[NH2:2].[CH2:10]([CH2:17][C:18](=O)[CH3:19])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[CH3:19][C:18](=[N:2][NH:1][C:3]1[CH:8]=[CH:7][NH:6][C:5](=[O:9])[CH:4]=1)[CH2:17][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

참가 물질

3

반응물 2

HCID 17355Benzyl acetoneHCID 136108294-Hydrazinylpyridin-2(1H)-one

생성물 1

HCID 714120494-[2-(4-Phenylbutan-2-ylidene)hydrazinyl]pyridin-2(1H)-one

실험 절차

In accordance with the same procedures as in Step 2 of Preparation 1, except for using 4-hydrazino-1H-pyridin-2-one (5.39 g, 43.1 mmol) prepared in Step 1 of Preparation 1 and benzylacetone (9.70 ml, 64.6 mmol), the titled compound was obtained as a white solid. (Yield: 66.5%) The product was used in the subsequent reaction without further purification.

후처리

  1. customIn accordance with the same procedures as in Step 2 of Preparation 1

출처 및 근거

ORD 기록
ord-35de0e18615f4d3f9fefef6ef3bcfadf
출처 데이터셋
uspto-grants-2012_04
특허 번호
US08148529B2

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