2-Chloro-1-fluoro-4-methylsulfonylbenzene → 2-{4-Chloro-3-[2-chloro-4-(methylsulfonyl)phenoxy]phenyl}propanoic acid

HRID 1686384노트

반응식

HRID 1686384 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH3:13])[C:9]([O:11]C)=[O:10])=[CH:4][C:3]=1[OH:14].[CH3:15][S:16]([C:19]1[CH:24]=[CH:23][C:22](F)=[C:21]([Cl:26])[CH:20]=1)(=[O:18])=[O:17]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH3:13])[C:9]([OH:11])=[O:10])=[CH:4][C:3]=1[O:14][C:22]1[CH:23]=[CH:24][C:19]([S:16]([CH3:15])(=[O:18])=[O:17])=[CH:20][C:21]=1[Cl:26]

참가 물질

3

반응물 2

HCID 213408802-Chloro-1-fluoro-4-methylsulfonylbenzeneHCID 67266160Methyl 2-(4-chloro-3-hydroxyphenyl)propanoate

생성물 1

HCID 161246342-{4-Chloro-3-[2-chloro-4-(methylsulfonyl)phenoxy]phenyl}propanoic acid

실험 절차

The title compound was prepared by the method of example 2 step (iii) using the product of step (iii) and 3-chloro-4-fluorophenyl methyl sulfone.

출처 및 근거

ORD 기록
ord-8304a57557054ede908e66c562b4925f
출처 데이터셋
uspto-grants-2012_04
특허 번호
US08148572B2

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