2-(3-Chloro-5-hydroxyphenyl)acetic acid → {3-Chloro-5-[2-chloro-4-(phenylsulfonyl)phenoxy]phenyl}acetic acid

반응식

[C:1]1([S:7]([C:10]2[CH:15]=[CH:14][C:13](F)=[C:12]([Cl:17])[CH:11]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:18][C:19]1[CH:20]=[C:21]([CH2:26][C:27]([OH:29])=[O:28])[CH:22]=[C:23]([OH:25])[CH:24]=1>>[Cl:18][C:19]1[CH:20]=[C:21]([CH2:26][C:27]([OH:29])=[O:28])[CH:22]=[C:23]([O:25][C:13]2[CH:14]=[CH:15][C:10]([S:7]([C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)(=[O:9])=[O:8])=[CH:11][C:12]=2[Cl:17])[CH:24]=1

참가 물질

반응물 2

HCID 596446192-(3-Chloro-5-hydroxyphenyl)acetic acid

HCID 689525093-Chloro-4-fluorophenyl phenyl sulfone

생성물 1

HCID 16123207{3-Chloro-5-[2-chloro-4-(phenylsulfonyl)phenoxy]phenyl}acetic acid

실험 절차

The title compound was prepared by the method of example 2 step (iii) using the product of step (i) and the product of example 18 step (iv).

출처 및 근거

ORD 기록: ord-babe695ea1d541629ed59d62b4cbdd7c
출처 데이터셋: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08148572B2

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