2-Chloro-5-(ethylsulfonyl)benzonitrile → [3-[2-Cyano-4-(ethylsulfonyl)phenoxy]-5-(trifluoromethyl)phenyl]acetic acid

HRID 1686418

반응식

HRID 1686418 반응식
[OH:1][C:2]1[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.Cl[C:17]1[CH:24]=[CH:23][C:22]([S:25]([CH2:28][CH3:29])(=[O:27])=[O:26])=[CH:21][C:18]=1[C:19]#[N:20]>>[C:19]([C:18]1[CH:21]=[C:22]([S:25]([CH2:28][CH3:29])(=[O:27])=[O:26])[CH:23]=[CH:24][C:17]=1[O:1][C:2]1[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:9])([F:10])[F:11])[CH:7]=1)#[N:20]

참가 물질

3

반응물 2

HCID 673903892-Chloro-5-(ethylsulfonyl)benzonitrileHCID 690656243-Hydroxy-5-(trifluoromethyl)phenylacetic acid

생성물 1

HCID 16123318[3-[2-Cyano-4-(ethylsulfonyl)phenoxy]-5-(trifluoromethyl)phenyl]acetic acid

실험 절차

The title compound was prepared as described in example 2 step (iii) but instead using the product from example 25 step (iv) and the product from example 12 step (i).

출처 및 근거

ORD 기록
ord-5b614919e27a463f83e3ac781e7fc9ec
출처 데이터셋
uspto-grants-2012_04
특허 번호
US08148572B2

연결된 노트

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