2-Chloro-4-(ethylsulfonyl)-1-fluorobenzene → {3-Bromo-5-[2-chloro-4-(ethylsulfonyl)phenoxy]phenyl}acetic acid

반응식

[Br:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([OH:12])=[O:11])[CH:5]=[C:6]([OH:8])[CH:7]=1.[CH2:13]([S:15]([C:18]1[CH:23]=[CH:22][C:21](F)=[C:20]([Cl:25])[CH:19]=1)(=[O:17])=[O:16])[CH3:14]>>[Br:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([OH:12])=[O:11])[CH:5]=[C:6]([O:8][C:21]2[CH:22]=[CH:23][C:18]([S:15]([CH2:13][CH3:14])(=[O:17])=[O:16])=[CH:19][C:20]=2[Cl:25])[CH:7]=1

참가 물질

반응물 2

HCID 579047252-Chloro-4-(ethylsulfonyl)-1-fluorobenzene

HCID 667341662-(3-Bromo-5-hydroxyphenyl)acetic acid

생성물 1

HCID 57791934{3-Bromo-5-[2-chloro-4-(ethylsulfonyl)phenoxy]phenyl}acetic acid

실험 절차

The title compound was prepared as described in example 2 step (iii) but instead using the product from step (v) and the product from example 3 step (i).

출처 및 근거

ORD 기록: ord-1893df8f72a542948c49bfc87ff9e937
출처 데이터셋: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08148572B2

반응 노트

불러오는 중…