Methyl 3-bromo-5-hydroxybenzoate → Methyl 3-bromo-5-[2-chloro-4-(ethylsulfonyl)phenoxy]benzoate

반응식

[Br:1][C:2]1[CH:3]=[C:4]([CH:9]=[C:10]([OH:12])[CH:11]=1)[C:5]([O:7][CH3:8])=[O:6].[CH2:13]([S:15]([C:18]1[CH:23]=[CH:22][C:21](F)=[C:20]([Cl:25])[CH:19]=1)(=[O:17])=[O:16])[CH3:14]>>[Br:1][C:2]1[CH:3]=[C:4]([CH:9]=[C:10]([O:12][C:21]2[CH:22]=[CH:23][C:18]([S:15]([CH2:13][CH3:14])(=[O:17])=[O:16])=[CH:19][C:20]=2[Cl:25])[CH:11]=1)[C:5]([O:7][CH3:8])=[O:6]

참가 물질

반응물 2

HCID 53216607Methyl 3-bromo-5-hydroxybenzoate

HCID 579047252-Chloro-4-(ethylsulfonyl)-1-fluorobenzene

생성물 1

HCID 67265867Methyl 3-bromo-5-[2-chloro-4-(ethylsulfonyl)phenoxy]benzoate

실험 절차

The subtitle compound was prepared as described in example 2 step (iii) but instead using the product from step (i) and the product from example 3 step (i).

출처 및 근거

ORD 기록: ord-3ddf4ae7547741d69ddd3fe4438b4feb
출처 데이터셋: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08148572B2

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