3-Hydroxy-5-(trifluoromethyl)phenylacetic acid → [3-{[3-Methyl-5-(phenylsulfonyl)pyridin-2-yl]oxy}-5-(trifluoromethyl)phenyl]acetic acid
반응식
[OH:1][C:2]1[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.Cl[C:17]1[C:22]([CH3:23])=[CH:21][C:20]([S:24]([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)(=[O:26])=[O:25])=[CH:19][N:18]=1>>[CH3:23][C:22]1[C:17]([O:1][C:2]2[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:9])([F:10])[F:11])[CH:7]=2)=[N:18][CH:19]=[C:20]([S:24]([C:27]2[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=2)(=[O:26])=[O:25])[CH:21]=1참가 물질
3
실험 절차
The title compound was prepared as described in example 2 step (iii) but instead using the product from example 25 step (iv) and the product from step (ii).
출처 및 근거
- ORD 기록
- ord-e8d2a4973d84407c927abfacc10b7587
- 출처 데이터셋
- uspto-grants-2012_04