Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Morpholine → 4-[(3-Chloro-4-fluorophenyl)sulfonyl]morpholine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Morpholine | HCID 8083 | — |
| 반응물 | 3-Chloro-4-fluorobenzenesulphonyl chloride | HCID 145222 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-[(3-Chloro-4-fluorophenyl)sulfonyl]morpholine | HCID 697826 | — |
반응 단계
4-fluoro-3-chlorobenzenesulphonyl chloride (0.9 g) was stirred in dry DCM (10 ml) and morpholine (0.69 ml) added. The mixture was allowed to stir at RT for 1 h and then quenched with water, extracted with DCM, dried (MgSO4) and evaporated under reduced pressure to give a white solid (1.10 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08148572B2 |
| 출처 데이터셋 | uspto-grants-2012_04 |
| ORD ID | ord-9630a25f50aa454dade9a9dfd6f7ac7e |
| 출처 메모 | uspto-grants-2012_04 |