4-[(3-Chloro-4-fluorophenyl)sulfonyl]morpholine → [3-[2-Chloro-4-(morpholin-4-ylsulfonyl)phenoxy]-5-(trifluoromethyl)phenyl]acetic acid

HRID 1686446

반응식

HRID 1686446 반응식
[OH:1][C:2]1[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.[Cl:16][C:17]1[CH:18]=[C:19]([S:24]([N:27]2[CH2:32][CH2:31][O:30][CH2:29][CH2:28]2)(=[O:26])=[O:25])[CH:20]=[CH:21][C:22]=1F>>[Cl:16][C:17]1[CH:18]=[C:19]([S:24]([N:27]2[CH2:32][CH2:31][O:30][CH2:29][CH2:28]2)(=[O:26])=[O:25])[CH:20]=[CH:21][C:22]=1[O:1][C:2]1[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:9])([F:10])[F:11])[CH:7]=1

참가 물질

3

반응물 2

HCID 6978264-[(3-Chloro-4-fluorophenyl)sulfonyl]morpholineHCID 690656243-Hydroxy-5-(trifluoromethyl)phenylacetic acid

생성물 1

HCID 16123657[3-[2-Chloro-4-(morpholin-4-ylsulfonyl)phenoxy]-5-(trifluoromethyl)phenyl]acetic acid

실험 절차

The title compound was prepared as described in example 2 step (iii) but instead using the product from example 25 step (iv) and the product from step (i).

출처 및 근거

ORD 기록
ord-2a74c3d3267f4820b83a056edc848580
출처 데이터셋
uspto-grants-2012_04
특허 번호
US08148572B2

연결된 노트

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