2-(3-Chloro-5-hydroxyphenyl)acetic acid → {3-Chloro-5-[4-(ethylsulfonyl)-3-(trifluoromethyl)phenoxy]phenyl}acetic acid

HRID 1686452

반응식

HRID 1686452 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([OH:12])=[O:11])[CH:5]=[C:6]([OH:8])[CH:7]=1.Br[C:14]1[CH:19]=[CH:18][C:17]([S:20]([CH2:23][CH3:24])(=[O:22])=[O:21])=[C:16]([C:25]([F:28])([F:27])[F:26])[CH:15]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([OH:12])=[O:11])[CH:5]=[C:6]([O:8][C:14]2[CH:19]=[CH:18][C:17]([S:20]([CH2:23][CH3:24])(=[O:21])=[O:22])=[C:16]([C:25]([F:27])([F:28])[F:26])[CH:15]=2)[CH:7]=1

참가 물질

3

반응물 2

HCID 596446192-(3-Chloro-5-hydroxyphenyl)acetic acidHCID 689507534-Bromo-1-(ethylsulfonyl)-2-(trifluoromethyl)benzene

생성물 1

HCID 16123768{3-Chloro-5-[4-(ethylsulfonyl)-3-(trifluoromethyl)phenoxy]phenyl}acetic acid

실험 절차

The title compound was prepared as described in example 2 step (iii) but instead using the product from example 18 step (iv) and the product from step (i).

출처 및 근거

ORD 기록
ord-f03c9d2936504c9a9f09345dff74b8b9
출처 데이터셋
uspto-grants-2012_04
특허 번호
US08148572B2

연결된 노트

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