2-Methyl-4-nitrobenzamide → 4-Amino-2-methylbenzamide

HRID 1690264노트

반응식

HRID 1690264 반응식
[CH3:1][C:2]1[CH:10]=[C:9]([N+:11]([O-])=O)[CH:8]=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5]>CCO.[Pd]>[NH2:11][C:9]1[CH:8]=[CH:7][C:3]([C:4]([NH2:6])=[O:5])=[C:2]([CH3:1])[CH:10]=1

참가 물질

4

반응물 1

HCID 201651202-Methyl-4-nitrobenzamide

생성물 1

HCID 230682064-Amino-2-methylbenzamide

시약·촉매·용매 2

HCID 702Ethanol용매HCID 23938Palladium용매

실험 절차

2-methyl-4-nitrobenzamide (E111) was dissolved in EtOH under Ar and 10% Pd/C added. The reaction was pump-purged with H2 and left stirring at room temperature overnight. The catalyst was removed by filtration and the reaction concentrated to give pure 4-amino-2-methylbenzamide (E112).

후처리

  1. additionadded
  2. customThe reaction was pump-purged with H2
  3. waitleft
  4. customThe catalyst was removed by filtration
  5. concentrationthe reaction concentrated

출처 및 근거

ORD 기록
ord-7d3c67d88da14815b641048464c94aa0
출처 데이터셋
uspto-grants-2012_04
특허 번호
US08153656B2

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