Dimethylamine → HCID 59618766, 화합물

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[CH3:1][C:2]([C:7]1[CH:8]=[CH:9][C:10]2[NH:16][C:15]3[N:17]=[C:18]([C:21]([F:24])([F:23])[F:22])[CH:19]=[CH:20][C:14]=3[CH2:13][N:12]([S:25]([C:28]3[CH:33]=[CH:32][C:31]([O:34][C:35]([F:38])([F:37])[F:36])=[CH:30][CH:29]=3)(=[O:27])=[O:26])[C:11]=2[CH:39]=1)([CH3:6])[C:3]([OH:5])=O.[CH3:40][NH:41][CH3:42]>>[CH3:40][N:41]([CH3:42])[C:3](=[O:5])[C:2]([CH3:6])([C:7]1[CH:8]=[CH:9][C:10]2[NH:16][C:15]3[N:17]=[C:18]([C:21]([F:23])([F:22])[F:24])[CH:19]=[CH:20][C:14]=3[CH2:13][N:12]([S:25]([C:28]3[CH:29]=[CH:30][C:31]([O:34][C:35]([F:36])([F:37])[F:38])=[CH:32][CH:33]=3)(=[O:27])=[O:26])[C:11]=2[CH:39]=1)[CH3:1]

참가 물질

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HCID 674Dimethylamine

HCID 59618649HCID 59618649, 화합물

생성물 1

HCID 59618766HCID 59618766, 화합물

실험 절차

The title compound was prepared from 2-methyl-2-[6-{[4-(trifluoromethoxy)phenyl]sulfonyl}-2-(trifluoromethyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-8-yl]propanoic acid (Example 382) and dimethylamine using the procedure described in Example 516 to afford the title compound; Mass Spectrum: m/e=603 (M+1).

출처 및 근거

ORD 기록: ord-8487f508ae114e32bb09e102647316d1
출처 데이터셋: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08153626B2

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