4-Bromoaniline → HCID 57897867, 화합물
반응식
[Br:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.[Cl:9][C:10]1[CH:18]=[C:17]([Cl:19])[CH:16]=[CH:15][C:11]=1[C:12]([Cl:14])=O.C(N(CC)CC)C>ClCCl>[Br:1][C:2]1[CH:8]=[CH:7][C:5]([N:6]=[C:12]([Cl:14])[C:11]2[CH:15]=[CH:16][C:17]([Cl:19])=[CH:18][C:10]=2[Cl:9])=[CH:4][CH:3]=1참가 물질
5
실험 절차
To a solution of 4-bromoaniline (40 mg, 0.12 mmol) and 2,4-dichloro benzoyl chloride (69 μL, 0.12 mmol) in dichloromethane is added triethylamine (20 μL, 0.144 mmol). After stirred at room temperature for 30 min, the solvent is removed. The residue is added 0.5 mL of thionyl chloride. The reaction mixture is heated at 80° C. for 1h, concentrated. The product is used in the next step reaction.
후처리
- customthe solvent is removed
- additionThe residue is added 0.5 mL of thionyl chloride
- temperatureThe reaction mixture is heated at 80° C. for 1h
- concentrationconcentrated
- customThe product is used in the next step reaction
출처 및 근거
- ORD 기록
- ord-e7105121bd034c838f6bb62745f4efea
- 출처 데이터셋
- uspto-grants-2012_04
- 특허 번호
- US08158634B2
반응 노트
불러오는 중…