Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isoamyl Nitrite → 2-Chloro-4-(ethylthio)-1-iodo-benzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isoamyl Nitrite | HCID 8053 | — |
| 반응물 | Diethyl disulfide | HCID 8077 | — |
| 반응물 | 3-Chloro-4-iodoaniline | HCID 282926 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 2-Chloro-4-(ethylthio)-1-iodo-benzene | HCID 67280185 | — |
반응 단계
A solution of 3-chloro-4-iodo-aniline (5.6 g), isoamylnitrite (8.8 ml) and ethyldisulphide (13.4 ml) in acetonitrile (100 ml) was heated at 60° C. for 24 h. The solvent was removed under reduced pressure and the residue purified by chromatography on silica eluting with 1% ethylacetate/isohexane. Yield 4.02 g
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08158820B2 |
| 출처 데이터셋 | uspto-grants-2012_04 |
| ORD ID | ord-7c48071fe59d41d998676c0323da739d |
| 출처 메모 | uspto-grants-2012_04 |