HCID 67277101, 화합물 → 2-[[2'-Chloro-4'-[(dimethylamino)sulfonyl]-5-(trifluoromethyl)[1,1'-biphenyl]-2-yl]oxy]-(2S)-propanoic acid

HRID 1694744

반응식

HRID 1694744 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([S:9]([N:12]([CH3:14])[CH3:13])(=[O:11])=[O:10])[CH:5]=[CH:6][C:7]=1I.B([C:18]1[CH:29]=[C:28]([C:30]([F:33])([F:32])[F:31])[CH:27]=[CH:26][C:19]=1[O:20][C@@H:21]([CH3:25])[C:22]([OH:24])=[O:23])(O)O>>[Cl:1][C:2]1[CH:3]=[C:4]([S:9]([N:12]([CH3:14])[CH3:13])(=[O:11])=[O:10])[CH:5]=[CH:6][C:7]=1[C:26]1[CH:27]=[C:28]([C:30]([F:33])([F:32])[F:31])[CH:29]=[CH:18][C:19]=1[O:20][C@@H:21]([CH3:25])[C:22]([OH:24])=[O:23]

참가 물질

3

반응물 2

HCID 67277101HCID 67277101, 화합물HCID 672802043-Chloro-4-iodo-N,N-dimethylbenzenesulfonamide

생성물 1

HCID 114764922-[[2'-Chloro-4'-[(dimethylamino)sulfonyl]-5-(trifluoromethyl)[1,1'-biphenyl]-2-yl]oxy]-(2S)-propanoic acid

실험 절차

The title compound was prepared by the method of example 144 step (i) using the product from step (ii) and the product from example 146 step (iv).

출처 및 근거

ORD 기록
ord-9dd2adb4d5c140d6955b8e9b625e2da3
출처 데이터셋
uspto-grants-2012_04
특허 번호
US08158820B2

연결된 노트

불러오는 중…