(2S)-2-[2-borono-4-(trifluoromethyl)phenoxy]-propanoic acid → HCID 11246757, 화합물

HRID 1694745노트

반응식

HRID 1694745 반응식
FC(F)(F)S(O[C:7]1[CH:12]=[CH:11][C:10]([S:13]([CH3:16])(=[O:15])=[O:14])=[CH:9][C:8]=1[F:17])(=O)=O.B([C:23]1[CH:34]=[C:33]([C:35]([F:38])([F:37])[F:36])[CH:32]=[CH:31][C:24]=1[O:25][C@@H:26]([CH3:30])[C:27]([OH:29])=[O:28])(O)O>>[F:17][C:8]1[CH:9]=[C:10]([S:13]([CH3:16])(=[O:14])=[O:15])[CH:11]=[CH:12][C:7]=1[C:31]1[CH:32]=[C:33]([C:35]([F:38])([F:37])[F:36])[CH:34]=[CH:23][C:24]=1[O:25][C@@H:26]([CH3:30])[C:27]([OH:29])=[O:28]

참가 물질

3

반응물 2

HCID 67277101(2S)-2-[2-borono-4-(trifluoromethyl)phenoxy]-propanoic acidHCID 86006151HCID 86006151, 화합물

생성물 1

HCID 11246757HCID 11246757, 화합물

실험 절차

The title compound was prepared by the method of example 144 step (i) using the product from step (i) and the product from example 146 step (iv).

출처 및 근거

ORD 기록
ord-b5115e02e02f49cd80dd9f3c0c4aa9c4
출처 데이터셋
uspto-grants-2012_04
특허 번호
US08158820B2

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