Methyl 2-(difluoromethoxy)benzoate → 3-[2-(Difluoromethoxy)phenyl]-3-oxopropanenitrile
반응식
[NH2:1][C:2]1[CH:6]=CNN=1.CO[C:9](=[O:20])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[O:16][CH:17]([F:19])[F:18]>>[F:19][CH:17]([F:18])[O:16][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=1[C:9](=[O:20])[CH2:6][C:2]#[N:1]참가 물질
3
실험 절차
The product was prepared according to the general procedure for aminopyrazole synthesis from 1.5 g (7.4 mmol, 1.0 eq) of 2-Difluoromethoxy-benzoic acid methyl ester (route A1bis). The crude product was used directly for the next step.
후처리
- customThe product was prepared
출처 및 근거
- ORD 기록
- ord-0f15433e20a74235b1d0fedbee0f400f
- 출처 데이터셋
- uspto-grants-2012_04
- 특허 번호
- US08163729B2
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