Sodium Carbonate → N-{6-[5-Amino-6-(methyloxy)-3-pyridinyl]-1-[(4-methylphenyl)sulfonyl]-1H-indazol-4-yl}-2-{[(2R,6S)-2,6-dimethyl-4-morpholinyl]methyl}-1,3-thiazole-4-carboxamide

반응식

Br[C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[N:7][N:8]2[S:11]([C:14]2[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][CH:15]=2)(=[O:13])=[O:12])=[C:4]([NH:21][C:22]([C:24]2[N:25]=[C:26]([CH2:29][N:30]3[CH2:35][C@H:34]([CH3:36])[O:33][C@H:32]([CH3:37])[CH2:31]3)[S:27][CH:28]=2)=[O:23])[CH:3]=1.[CH3:38][O:39][C:40]1[C:45]([NH2:46])=[CH:44][C:43](B2OC(C)(C)C(C)(C)O2)=[CH:42][N:41]=1.C(=O)([O-])[O-].[Na+].[Na+].O1CCOCC1>C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2].C(Cl)Cl.O>[NH2:46][C:45]1[CH:44]=[C:43]([C:2]2[CH:10]=[C:9]3[C:5]([CH:6]=[N:7][N:8]3[S:11]([C:14]3[CH:15]=[CH:16][C:17]([CH3:20])=[CH:18][CH:19]=3)(=[O:12])=[O:13])=[C:4]([NH:21][C:22]([C:24]3[N:25]=[C:26]([CH2:29][N:30]4[CH2:35][C@H:34]([CH3:36])[O:33][C@H:32]([CH3:37])[CH2:31]4)[S:27][CH:28]=3)=[O:23])[CH:3]=2)[CH:42]=[N:41][C:40]=1[O:39][CH3:38]