Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1695963생성일: 2026년 10월 26일
Ethanol → 4-(3-Isoxazol-5-yl-5-oxo-2,5-dihydro-pyrazol-1-yl)-N-(1,2,2,6,6-pentamethyl-piperidin-4-yl)-benzamide
https://huagongshe.com/reaction/1695963
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | 4-Hydrazino-N-(1,2,2,6,6-pentamethyl-piperidin-4-yl)-benzamide | HCID 59515576 | — |
| 반응물 | 3-Isoxazol-5-yl-3-oxo-propionic acid ethyl ester | HCID 59515581 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 4-(3-Isoxazol-5-yl-5-oxo-2,5-dihydro-pyrazol-1-yl)-N-(1,2,2,6,6-pentamethyl-piperidin-4-yl)-benzamide | HCID 59515579 | — |
반응 단계
3-Isoxazol-5-yl-3-oxo-propionic acid ethyl ester (49 mg) and 4-Hydrazino-N-(1,2,2,6,6-pentamethyl-piperidin-4-yl)-benzamide (93 mg) were dissolved into ethanol (2.5 ml) and acetic acid (0.3 ml) and the solution stirred at 65° C. for 2 h. Concentration in vacuo and purification by HPLC gave the expected product. LC/MS: main peak is product (m/z: 424.3)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US08163757B2 |
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| 출처 데이터셋 | uspto-grants-2012_04 |
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| ORD ID | ord-b749f24f24fe4fcba056b5e8b41063bc |
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| 출처 메모 | uspto-grants-2012_04 |
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