참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 4-Chlorophenyl Isocyanate | HCID 7693 | — |
| 반응물 | Benzaldehyde, 3-amino- | HCID 74366 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | N-(4-Chlorophenyl)-N'-(3-formylphenyl)urea | HCID 71423985 | — |
반응 단계
a mixture of 360 mg of 3-aminobenzaldehyde (0.3 mmoles) and 460 mg of 4-chloro-phenylisocyanate (0.3 mmoles) in 3 ml of DMF is heated under microwave irradiation at 110° C. for 10 minutes. The precipitate formed is filtered giving the desired 1-(4-Chloro-phenyl)-3-(3-formyl-phenyl)-urea. Analytical LC/MS method A: ([M+H]+): 351, RT: 5.30 min (gradient 5 to 85% acetonitrile in 7 min).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08163768B2 |
|---|
| 출처 데이터셋 | uspto-grants-2012_04 |
|---|
| ORD ID | ord-db28fdc86fd541bca671c216e2d4f2cd |
|---|
| 출처 메모 | uspto-grants-2012_04 |
|---|
