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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1697184생성일: 2026년 10월 26일

4-Iodo-2-(trifluoromethyl)pyridine → (S)-Methyl2-(tert-butoxycarbonyl)-3-(2-(trifluoromethyl)pyridin-4-yl)propanoate

https://huagongshe.com/reaction/1697184

반응식

참여 물질

역할이름HCID투입량
반응물4-Iodo-2-(trifluoromethyl)pyridineHCID 23436940—
반응물(R)-methyl2-(tert-butoxycarbonyl)-3-iodopropanoateHCID 86614124—
생성물(S)-Methyl2-(tert-butoxycarbonyl)-3-(2-(trifluoromethyl)pyridin-4-yl)propanoateHCID 67165305—

반응 단계

The title compound was prepared according to previously reported procedure (see pending U.S. patent application Ser. No. 11/575,187) from (R)-methyl 2-(tert-butoxycarbonyl)-3-iodopropanoate and 4-iodo-2-(trifluoromethyl)pyridine (this starting material was prepared according to a procedure described in Eur. J. Org. Chem. 2003, 1559-1568).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08163909B2
출처 데이터셋uspto-grants-2012_04
ORD IDord-cbebf66771c04952bc7e7dd7c5332e4f
출처 메모uspto-grants-2012_04