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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1697573생성일: 2026년 10월 26일

Tert-butyl acetoacetate → (2S,4R)-4-(4-Fluoro-2-trifluoromethyl-benzenesulfonyl)-1-(3-oxo-butyryl)-pyrrolidine-2-carboxylic Acid Methyl Ester

https://huagongshe.com/reaction/1697573

반응식

참여 물질

역할이름HCID투입량
반응물Tert-butyl acetoacetateHCID 15538—
반응물(2S,4R)-4-(4-Fluoro-2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic Acid Methyl EsterHCID 66770389—
생성물(2S,4R)-4-(4-Fluoro-2-trifluoromethyl-benzenesulfonyl)-1-(3-oxo-butyryl)-pyrrolidine-2-carboxylic Acid Methyl EsterHCID 86646828—

반응 단계

In analogy to the procedure described in example 192f, (2S,4R)-4-(4-fluoro-2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid methyl ester was reacted with tert-butyl acetoacetate to give the title compound as yellow oil. MS (ESI): m/z=440.2 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08163793B2
출처 데이터셋uspto-grants-2012_04
ORD IDord-6d4ddc6c4d054ccea558605a33dfa90f
출처 메모uspto-grants-2012_04