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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1697574생성일: 2026년 10월 26일

Lawesson's reagent → (2S,4R)-4-(4-Fluoro-2-trifluoromethyl-benzenesulfonyl)-1-(3-oxo-thiobutyryl)-pyrrolidine-2-carboxylic Acid Methyl Ester

https://huagongshe.com/reaction/1697574

반응식

참여 물질

역할이름HCID투입량
반응물Lawesson's reagentHCID 87949—
반응물(2S,4R)-4-(4-Fluoro-2-trifluoromethyl-benzenesulfonyl)-1-(3-oxo-butyryl)-pyrrolidine-2-carboxylic Acid Methyl EsterHCID 86646828—
생성물(2S,4R)-4-(4-Fluoro-2-trifluoromethyl-benzenesulfonyl)-1-(3-oxo-thiobutyryl)-pyrrolidine-2-carboxylic Acid Methyl EsterHCID 86646829—

반응 단계

In analogy to the procedure described in example 192 g, (2S,4R)-4-(4-fluoro-2-trifluoromethyl-benzenesulfonyl)-1-(3-oxo-butyryl)-pyrrolidine-2-carboxylic acid methyl ester was reacted with Lawesson's reagent to give the title compound as brown solid.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08163793B2
출처 데이터셋uspto-grants-2012_04
ORD IDord-39a775a35ee147d8b5c240a804fbe67e
출처 메모uspto-grants-2012_04