Bromocyclopentane → Ethyl 2-Cyclopentylhexan-3-onecarboxylate

HRID 1698847노트

반응식

[CH2:1]([C:8]([O:10][CH2:11][CH3:12])=[O:9])[CH2:2][C:3](=[O:7])[CH2:4][CH2:5][CH3:6].Br[CH:14]1[CH2:18][CH2:17][CH2:16][CH2:15]1>>[CH:14]1([CH:2]([C:3](=[O:7])[CH2:4][CH2:5][CH3:6])[CH2:1][C:8]([O:10][CH2:11][CH3:12])=[O:9])[CH2:18][CH2:17][CH2:16][CH2:15]1

참가 물질

반응물 2

HCID 8728Bromocyclopentane

HCID 12271529Ethyl 4-oxoheptanoate

생성물 1

HCID 18322313Ethyl 2-Cyclopentylhexan-3-onecarboxylate

실험 절차

The preparation was carried out analogously to Example I from 4.04 g (25.0 mmol) of ethyl hexan-3-onecarboxylate and 2.95 ml (4.10 g, 27.3 mmol) of bromocyclopentane. Purification was carried out chromatographically (silica gel, petroleum ether: ethyl acetate 20:1). MS (EI): 226 [M]+.

후처리

customPurification

출처 및 근거

ORD 기록: ord-e9822307f48d44ac8c9686a642d0afb8
출처 데이터셋: uspto-grants-2002_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06344471B1

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