Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Bromo-1-(2-chloro-4-methoxyphenyl)-propan-1-one → 4-(2-Chloro-4-methoxyphenyl)-5-methyl-2-[N-(5-carboxy-2-methoxyphenyl)-N-propylamino]thiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Bromo-1-(2-chloro-4-methoxyphenyl)-propan-1-one | HCID 11054985 | — |
| 반응물 | N-(2-methoxy-5-carboxyphenyl)-N-propylthiourea | HCID 18322253 | — |
| 생성물 | 4-(2-Chloro-4-methoxyphenyl)-5-methyl-2-[N-(5-carboxy-2-methoxyphenyl)-N-propylamino]thiazole | HCID 18322262 | 70% |
반응 단계
By following the procedure of EXAMPLE 2 and by using 2-bromo-1-(2-chloro-4-methoxyphenyl)propan-1-one (Compound 1-2) and N-(2-methoxy-5-carboxyphenyl)-N-propylthiourea (Compound 12-1), the expected product is obtained in the form of white crystals; yield=70%; m.p.=109° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06344470B1 |
| 출처 데이터셋 | uspto-grants-2002_02 |
| ORD ID | ord-71231d9df8924d728346af42ac7d3379 |
| 출처 메모 | uspto-grants-2002_02 |