2-Fluoroanisole → 3'-Fluoro-2-(3-fluoro-4-methoxyphenyl)-4'-methoxyacetophenone

HRID 1699771노트

반응식

HRID 1699771 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH2:10][C:11]([OH:13])=O)[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].[F:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[O:21][CH3:22]>>[F:14][C:15]1[CH:20]=[C:19]([C:11](=[O:13])[CH2:10][C:4]2[CH:5]=[CH:6][C:7]([O:8][CH3:9])=[C:2]([F:1])[CH:3]=2)[CH:18]=[CH:17][C:16]=1[O:21][CH3:22]

참가 물질

3

반응물 2

HCID 675762-FluoroanisoleHCID 521176(3-Fluoro-4-methoxyphenyl)acetic acid

생성물 1

HCID 135263783'-Fluoro-2-(3-fluoro-4-methoxyphenyl)-4'-methoxyacetophenone수율 77.5%

실험 절차

Using 3-fluoro-4-methoxyphenylacetic acid and 2-fluoroanisole as starting materials, the procedures of Preparation Example 7 were repeated likewise, whereby the title compound was obtained in a yield of 77.5%.

후처리

  1. customthe procedures of Preparation Example 7

출처 및 근거

ORD 기록
ord-8883b50afb3941338f66cdcf644ebcd9
출처 데이터셋
uspto-grants-2002_02
특허 번호
US06348468B1

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