참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Nitrone | HCID 6350 | — |
| 반응물 | Nitrobenzene | HCID 7416 | — |
| 반응물 | 2,6-Lutidine | HCID 7937 | — |
| 반응물 | 4-[(2,4-dibromo-6-methylphenyl)diazenyl]-N,N-diethylaniline | HCID 12525527 | — |
| 촉매 | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| 생성물 | 4-(2'-cyano-4'-bromo-6'-methylphenylazo)-N,N-diethylaniline | HCID 20347455 | 15.1% |
반응 단계
A stirred mixture of 4-(2',4'-dibromo-6'-methylphenylazo)-N,N-diethylaniline (4.25 parts), copper (I) iodide (2.0 parts), formaldoxime trimer (1.75 parts), 2,6-lutidine (2.15 parts), and nitrobenzene (150 parts) was heated to 95° C. for 6 hours when thin layer chromatography showed reaction to be complete. The mixture was cooled, filtered and the nitrobenzene was removed by steam distillation. Crystallisation of the solid product from ethanol gave 4-(2'-cyano-4'-bromo-6'-methylphenylazo)-N,N-diethylaniline (Found: C, 58.2; H, 5.4; Br, 21.7; N, 15.2. C18H19BrN4 requires C, 58.2; H, 5.15; Br, 21.55; N, 15.1%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04192800 |
|---|
| 출처 데이터셋 | uspto-grants-1980_03 |
|---|
| ORD ID | ord-54d85bb108784b8bbeaa97feaa27ce35 |
|---|
| 출처 메모 | uspto-grants-1980_03 |
|---|
