Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → N-(2,6-Diisopropyl-phenyl)-N'-(3-trifluoromethyl-cyclohexyl)thiourea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 2-Isothiocyanato-1,3-bis(propan-2-yl)benzene | HCID 141194 | — |
| 반응물 | 3-(Trifluoromethyl)cyclohexylamine (cis-and trans-mixture) | HCID 16227766 | — |
| 생성물 | N-(2,6-Diisopropyl-phenyl)-N'-(3-trifluoromethyl-cyclohexyl)thiourea | HCID 20347045 | — |
반응 단계
16.0 g of 3-trifluoromethyl-cyclohexylamine are taken and 18.0 g of 2,6-diisopropyl-phenyl isothiocyanate are introduced whilst stirring. The reaction commences with slight evolution of heat. The mixture is left to stand for 12 hours and is then stirred with dilute hydrochloric acid. The crystalline product is filtered off, triturated with dilute methanol, filtered off and dried. The compound is obtained in the form of a stereomer mixture of melting point 67°-75° C.; yield 27 g. The elementary analysis and NMR and IR spectra agree with the assumed structure.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04194008 |
| 출처 데이터셋 | uspto-grants-1980_03 |
| ORD ID | ord-4ae2509c66324cd5a707c69dd2da05a1 |
| 출처 메모 | uspto-grants-1980_03 |