Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenolate Sodium → 3-(2,5-Hexadienoyloxy)-4-(3,3-dimethylcyclobutanecarbonyloxy)phenyl isopropylaminomethyl ketone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenolate Sodium | HCID 4445035 | — |
| 반응물 | Sodium Methoxide | HCID 10942334 | — |
| 반응물 | 3-Hydroxy-4-(3,3-dimethylcyclobutanecarbonyloxy)phenyl isopropylaminomethyl ketone | HCID 20535374 | — |
| 반응물 | 2,5-Hexadienoyl chloride | HCID 54421596 | — |
| 생성물 | 3-(2,5-Hexadienoyloxy)-4-(3,3-dimethylcyclobutanecarbonyloxy)phenyl isopropylaminomethyl ketone | HCID 70552929 | — |
반응 단계
Following a procedure similar to that described in Example 2A above when 3-hydroxy- 4-(3,3-dimethylcyclobutanecarbonyloxy)phenyl isopropylaminomethyl ketone is interacted with one equivalent of sodium methoxide and the resulting sodium phenolate salt is reacted with 2,5-hexadienoyl chloride there is obtained 3-(2,5-hexadienoyloxy)-4-(3,3-dimethylcyclobutanecarbonyloxy)phenyl isopropylaminomethyl ketone which reacts with hydrochloric acid to yield the hydrochloride salt. When this hydrochloride is reduced with sodium borohydride, using a procedure similar to that described above in Example 30C, there is obtained 3-(2,5-hexadienoyloxy)-4-(3,3-dimethylcyclobutanecarbonyloxy)-alpha-(isopropylaminomethyl)benzyl alcohol hydrochloride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | USRE030241 |
| 출처 데이터셋 | uspto-grants-1980_03 |
| ORD ID | ord-b0ee2d0240c64340beef61669fa5b3a7 |
| 출처 메모 | uspto-grants-1980_03 |