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Water → Acetic acid, ((4-(3-furanylcarbonyl)-1-naphthalenyl)oxy)-

HRID 1701715
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인쇄 미리보기

반응식

HRID 1701715 반응식
[C:1]1([O:11][CH2:12][C:13]([O:15]CC)=[O:14])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[C:18](=[O:21])([O-])[O-].[K+].[K+].[OH2:24]>C(O)C>[O:24]1[CH:3]=[CH:2][C:1]([C:18]([C:4]2[C:5]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[C:1]([O:11][CH2:12][C:13]([OH:15])=[O:14])=[CH:2][CH:3]=2)=[O:21])=[CH:10]1
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

5

반응물 3

HCID 962WaterHCID 11430Potassium CarbonateHCID 1482829Ethyl 2-(naphthalen-1-yloxy)acetate

생성물 1

HCID 3052164Acetic acid, ((4-(3-furanylcarbonyl)-1-naphthalenyl)oxy)-

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

15 g of the ester obtained according to (a) are dissolved in 300 ml ethanol; after addition of 7.6 g potassium carbonate in solution in 25 ml water, the mixture is refluxed for 17 hours and the alcohol removed under reduced pressure. The residue is purified by dissolution in water; the final product is extracted from the aqueous phase after acidification. 12 g of the acid which, after recrystallisation from dichloroethane, melts at 177° C. are obtained.

후처리

  1. temperaturethe mixture is refluxed for 17 hours
  2. customthe alcohol removed under reduced pressure
  3. customThe residue is purified by dissolution in water
  4. extractionthe final product is extracted from the aqueous phase after acidification
  5. custom12 g of the acid which, after recrystallisation from dichloroethane, melts at 177° C.
  6. customare obtained

출처 및 근거

ORD 기록
ord-703fd5c5c37843c7b538caf41730490b
출처 데이터셋
uspto-grants-1980_03
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US04195093

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