Ammonia → 5-(N,N-diethylaminomethyl)-2-furamide

HRID 1701805노트

반응식

HRID 1701805 반응식
[CH2:1]([N:3]([CH2:6][C:7]1[O:11][C:10]([C:12]([O:14]CCCC)=O)=[CH:9][CH:8]=1)[CH2:4][CH3:5])[CH3:2].[NH3:19]>>[CH2:1]([N:3]([CH2:6][C:7]1[O:11][C:10]([C:12]([NH2:19])=[O:14])=[CH:9][CH:8]=1)[CH2:4][CH3:5])[CH3:2]

참가 물질

3

반응물 2

HCID 222AmmoniaHCID 20346152Butyl 5-[(diethylamino)methyl]furan-2-carboxylate

생성물 1

HCID 431321835-(N,N-diethylaminomethyl)-2-furamide

실험 절차

A mixture of 25.3 g (0.1 mole) of n-butyl 5-(N,N-diethylaminomethyl)-2-furoate is added to 50 ml of liquid ammonia in a pressure vessel. The mixture is held at 180° C. and 2000 pounds per square inch gage pressure for 8 hours. The mixture is cooled to ambient temperature and evaporated to dryness giving 5-(N,N-diethylaminomethyl)-2-furamide (m.p. 164°-165° C.).

후처리

  1. customis held at 180° C.
  2. customevaporated to dryness

출처 및 근거

ORD 기록
ord-eb85caa288a540a391469828a5b38c70
출처 데이터셋
uspto-grants-1980_03
특허 번호
US04195023

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