4-Bromophenacyl bromide → HCID 12953425, 화합물

HRID 1701941노트

반응식

HRID 1701941 반응식
[CH:1]1[C:6]([C:7]([CH2:9]Br)=O)=[CH:5][CH:4]=[C:3]([Br:11])[CH:2]=1.[CH2:12]([O:14][C:15](=[O:20])[CH2:16][C:17](=[S:19])[NH2:18])[CH3:13]>C(O)C>[CH2:12]([O:14][C:15](=[O:20])[CH2:16][C:17]1[S:19][CH:9]=[C:7]([C:6]2[CH:5]=[CH:4][C:3]([Br:11])=[CH:2][CH:1]=2)[N:18]=1)[CH3:13]

참가 물질

4

반응물 2

HCID 74544-Bromophenacyl bromideHCID 2771567ethyl 3-amino-3-thioxopropanoate

생성물 1

HCID 12953425HCID 12953425, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of p-α-dibromoacetophenone (13.9 g, 0.05 mole) and 2-thiocarbamoylacetic acid ethyl ester in ethanol (65 ml) was heated under reflux for 21/2 hours. On cooling, there was obtained the title compound (12.2 g) mp 189°-191° C. (dec). An analytical sample recrystallized from ethanol had mp 191°-193° C.

후처리

  1. temperaturewas heated
  2. temperatureunder reflux for 21/2 hours
  3. temperatureOn cooling

출처 및 근거

ORD 기록
ord-3806dce4ffa34b2c9de10aaeb6a92241
출처 데이터셋
uspto-grants-1983_04
특허 번호
US04379791

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