tert.-butyl (4S)-1-ethyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate → tert.-butyl (4S)-1-ethyl-2-oxo-imidazolidine-4-carboxylate

HRID 1702205노트

반응식

HRID 1702205 반응식
[CH2:1]([N:3]1[CH2:7][C@@H:6]([C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])[N:5](C(OCC2C=CC=CC=2)=O)[C:4]1=[O:25])[CH3:2]>[Pd].CO>[CH2:1]([N:3]1[CH2:7][C@@H:6]([C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])[NH:5][C:4]1=[O:25])[CH3:2]

참가 물질

4

반응물 1

HCID 13053979tert.-butyl (4S)-1-ethyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate

생성물 1

HCID 13053981tert.-butyl (4S)-1-ethyl-2-oxo-imidazolidine-4-carboxylate수율 96.9%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

4.2 g of tert.-butyl (4S)-1-ethyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate, 0.1 g of palladium-black and 100 ml of methanol are treated in the same manner as described in Example 1-(3). 2.5 g of tert.-butyl (4S)-1-ethyl-2-oxo-imidazolidine-4-carboxylate are thereby obtained as colorless crystals. Yield: 96.9% M.p. 86°-87° C.

출처 및 근거

ORD 기록
ord-8bf79eef61a34ab79c62cc613db8a0a3
출처 데이터셋
uspto-grants-1983_04
특허 번호
US04380644

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