2-Phenyl-1,3-dioxan-5-yl 4-(hexadecylamino)hydrocinnamate → 2-Hydroxy-1-(hydroxymethyl)ethyl 4-(hexadecylamino)hydrocinnamate

HRID 1702685노트

반응식

HRID 1702685 반응식
[CH2:1]([NH:17][C:18]1[CH:40]=[CH:39][C:21]([CH2:22][CH2:23][C:24]([O:26][CH:27]2[CH2:32][O:31]C(C3C=CC=CC=3)[O:29][CH2:28]2)=[O:25])=[CH:20][CH:19]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[H][H]>[Pd].C(O)(=O)C>[CH2:1]([NH:17][C:18]1[CH:19]=[CH:20][C:21]([CH2:22][CH2:23][C:24]([O:26][CH:27]([CH2:28][OH:29])[CH2:32][OH:31])=[O:25])=[CH:39][CH:40]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

참가 물질

5

반응물 2

HCID 536327232-Phenyl-1,3-dioxan-5-yl 4-(hexadecylamino)hydrocinnamateHCID 178418361HCID 178418361, 화합물2회

생성물 1

HCID 540874802-Hydroxy-1-(hydroxymethyl)ethyl 4-(hexadecylamino)hydrocinnamate

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 176Acetic Acid용매

실험 절차

A mixture of 2-phenyl-1,3-dioxan-5-yl 4-(hexadecylamino)hydrocinnamate, 10% palladium-on-carbon and acetic acid is treated with hydrogen in a Parr apparatus at room temperature until hydrogen uptake ceases. The mixture is filtered and the filtrate is evaporated. Recrystallization of the residue from chloroform provides the title compound.

후처리

  1. filtrationThe mixture is filtered
  2. customthe filtrate is evaporated
  3. customRecrystallization of the residue from chloroform

출처 및 근거

ORD 기록
ord-725f4360b40c430493054031178b1f00
출처 데이터셋
uspto-grants-1982_09
특허 번호
US04348399

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