Pyridine → Tert-butyl 4-isocyanatobutanoate
반응식
C1(P(N=[N+]=[N-])(C2C=CC=CC=2)=[O:8])C=CC=CC=1.[C:18]([O:22][C:23](=[O:30])[CH2:24][CH2:25][CH2:26]C(O)=O)([CH3:21])([CH3:20])[CH3:19].[N:31]1[CH:36]=CC=CC=1>>[C:18]([O:22][C:23]([CH2:24][CH2:25][CH2:26][N:31]=[C:36]=[O:8])=[O:30])([CH3:19])([CH3:20])[CH3:21]참가 물질
4
반응 조건
- 온도
- 90 °C
실험 절차
Diphenylphosphoryl azide (12.25 g.) was added dropwise to a solution of glutaric acid mono-tert-butyl ester (8.38 g.) in dry pyridine (37 ml.) and stirred at 90° C. for 40 minutes to give 3-tert-butoxycarbonylpropyl isocyanate (I.R.: 2270 cm-1).
출처 및 근거
- ORD 기록
- ord-10d23f7a3bde446d811e62e74643a032
- 출처 데이터셋
- uspto-grants-1982_09
- 특허 번호
- US04349552
반응 노트
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