Potassium Hydroxide → CID 53688637

HRID 1702962노트

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HRID 1702962 반응식
[OH-].[K+].[CH3:3][C:4]([CH:11]([CH3:13])[CH3:12])=[CH:5][C:6]([O:8]CC)=[O:7]>S(=O)(=O)(O)O>[CH3:3][C:4]([CH:11]([CH3:13])[CH3:12])=[CH:5][C:6]([OH:8])=[O:7]

참가 물질

4

반응물 2

HCID 14797Potassium HydroxideHCID 281491Ethyl 3,4-dimethyl-2-pentenoate

생성물 1

HCID 53688637CID 53688637

시약·촉매·용매 1

HCID 1118Sulfuric Acid용매

반응 조건

온도
80 °C

실험 절차

A mixture of aqueous potassium hydroxide solution (0.5 N, 92 mL) and ethyl 3,4-dimethyl-2-pentenoate (XI, 5.5 g) was stirred at 80° C. for 17 hours until the oily supernatent layer disappeared. The reaction mixture was cooled, acidified with aqueous sulfuric acid, (0.5 N, ca. 100 mL), and extracted with ether. The ethereal layer was washed with water, dried over anhydrous magnesium sulfate, filtered, and evaporated under reduced pressure to afford 3,4-dimethyl-2-pentenoic acid as a yellow liquid (X, 4.1 g, 91%).

후처리

  1. temperatureThe reaction mixture was cooled
  2. extractionextracted with ether
  3. washThe ethereal layer was washed with water
  4. dry with materialdried over anhydrous magnesium sulfate
  5. filtrationfiltered
  6. customevaporated under reduced pressure

출처 및 근거

ORD 기록
ord-c7bd73a29c464802a1af2a564e5a2444
출처 데이터셋
uspto-grants-1982_09
특허 번호
US04350638

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