참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ammonium Acetate | HCID 517165 | — |
| 반응물 | 2-Hydroxy-2-(4-hydroxyphenyl)acetic acid, sodium salt hydrate | HCID 23698133 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | N-(4-Hydroxyphenyl)glycine | HCID 67149 | 67% |
반응 단계
A mixture of sodium p-hydroxymandelate monohydrate (1.04 g.), ammonium acetate (2.0 g.) and water (0.5 ml.) is stirred and heated under reflux (internal temperature 125° C.) for 2.5 hours. Water (3 ml.) is added to the thick slurry thus obtained, the mixture is cooled and filtered and the solid residue is washed twice with water and then with acetone. There is thus obtained p-hydroxyphenylglycine (0.56 g., 66% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04350826 |
|---|
| 출처 데이터셋 | uspto-grants-1982_09 |
|---|
| ORD ID | ord-5199c7298b8e4d23b317a13a977cf9e7 |
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| 출처 메모 | uspto-grants-1982_09 |
|---|
