Salicylamide → 2-Propoxybenzamide
반응식
[C:1]([NH2:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].C[O-].[Na+].I[CH2:15][CH2:16][CH3:17]>C(O)C>[CH2:15]([O:4][C:3]1[CH:5]=[CH:6][CH:7]=[CH:8][C:2]=1[C:1]([NH2:10])=[O:9])[CH2:16][CH3:17]참가 물질
5
실험 절차
A 130 gm portion of salicylamide in 500 ml. of ethanol is reacted with 52.4 gm. of sodium methoxide and 164.9 gm. of 1-iodopropane by heating at reflux. The mixture is cooled, precipitated in 1500 ml. of water and the solid is recrystallized from hot ethanol giving o-propoxybenzamide.
후처리
- temperatureat reflux
- temperatureThe mixture is cooled
- customprecipitated in 1500 ml
- customof water and the solid is recrystallized from hot ethanol
출처 및 근거
- ORD 기록
- ord-1c15088dbfb145e3b4a7f93c176ad759
- 출처 데이터셋
- uspto-grants-1978_11
- 특허 번호
- US04124766
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