Pyridine → 6-Hydroxy-3-hydroxycarbonyl-6-methyl-4-thiaundecanoic acid methyl ester

HRID 1703808

반응식

HRID 1703808 반응식
[CH3:1][O:2][C:3](=[O:9])/[CH:4]=[CH:5]\[C:6]([OH:8])=[O:7].[OH:10][C:11]([CH3:19])([CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH2:12][SH:13].N1C=CC=CC=1>C(Cl)Cl>[CH3:1][O:2][C:3](=[O:9])[CH2:4][CH:5]([C:6]([OH:8])=[O:7])[S:13][CH2:12][C:11]([OH:10])([CH3:19])[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

참가 물질

5

반응물 3

HCID 1049PyridineHCID 5354456Monomethyl maleateHCID 135068602-Methyl-1-sulfanylheptan-2-OL

생성물 1

HCID 544848136-Hydroxy-3-hydroxycarbonyl-6-methyl-4-thiaundecanoic acid methyl ester

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

A mixture of 2.6 g of maleic acid monomethyl ester, 3.2 g of 2-hydroxy-2-methylheptane-1-thiol, 0.5 ml of pyridine and 120 ml of methylene chloride is stirred for 3 hours at 30°. After the usual working up, 6-hydroxy-3-hydroxycarbonyl-6-methyl-4-thiaundecanoic acid methyl ester is obtained.

출처 및 근거

ORD 기록
ord-4520ee23d3ef460297e77c666abd1836
출처 데이터셋
uspto-grants-1978_11
특허 번호
US04125622

연결된 노트

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