Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromo-4'-chloro-3'-sulfamoylacetophenone → 3-Ethyl-4-(4-chloro-3-sulfamoylphenyl)-2-isopropylimino-1,3-thiazolidine-4-ol-hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bromo-4'-chloro-3'-sulfamoylacetophenone | HCID 12952390 | — |
| 반응물 | 1-Ethyl-3-isopropylthiourea | HCID 19650595 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 3-Ethyl-4-(4-chloro-3-sulfamoylphenyl)-2-isopropylimino-1,3-thiazolidine-4-ol-hydrochloride | HCID 22760539 | — |
반응 단계
6.2 g of 2-bromo-4'-chloro-3'-sulfamoylacetophenone and 2.92 g of 1-ethyl-3-isopropylthiourea were heated in 40 ml of acetone for 15 minutes to 40° C., the mixture was stirred for another 30 minutes at room temperature and the crystals were filtered. Colorless crystalline solid body: melting point: 188° C. (decomposition).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04125614 |
| 출처 데이터셋 | uspto-grants-1978_11 |
| ORD ID | ord-584a2bac8be64985bd13627ad0065a54 |
| 출처 메모 | uspto-grants-1978_11 |