Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N,N'-Diethylthiourea → 3-Ethyl-2-ethylimino-4-(4-methyl-3-sulfamoylphenyl)-1,3-thiazolidine-4-ol-hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N,N'-Diethylthiourea | HCID 2735009 | — |
| 반응물 | 2-Chloro-4'-methyl-3'-sulfamoylacetophenone | HCID 13628783 | — |
| 용매 | Diisopropyl Ether | HCID 7914 | — |
| 생성물 | 3-Ethyl-2-ethylimino-4-(4-methyl-3-sulfamoylphenyl)-1,3-thiazolidine-4-ol-hydrochloride | HCID 22760433 | — |
반응 단계
5 g of 2-chloro-4'-methyl-3'-sulfamoylacetophenone and 2.7 g of 1,3-diethylthiourea were reacted as prescribed in Example 12. After addition of 200 ml of diisopropyl ether the solvent was decanted and the oily end product was crystallized under ethyl acetate heated to 40° to 50° C. Colorless solid body, melting point: 160° C. (decomposition).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04125614 |
| 출처 데이터셋 | uspto-grants-1978_11 |
| ORD ID | ord-c4108d65d4e24c309ab0e54c0c8529d7 |
| 출처 메모 | uspto-grants-1978_11 |