Water → Acetamide, N-(2-(2-(2-cyano-4,6-dinitrophenyl)diazenyl)-5-(diethylamino)phenyl)-

HRID 1704199

반응식

HRID 1704199 반응식
[C:1]([NH:4][C:5]1[CH:6]=[C:7]([CH:13]=[CH:14][C:15]=1[N:16]=[N:17][C:18]1[C:23]([N+:24]([O-:26])=[O:25])=[CH:22][C:21]([N+:27]([O-:29])=[O:28])=[CH:20][C:19]=1Cl)[N:8]([CH2:11][CH3:12])[CH2:9][CH3:10])(=[O:3])[CH3:2].[C-:31]#[N:32].[Na+].O>C(CCSCCC#N)#N>[C:1]([NH:4][C:5]1[CH:6]=[C:7]([CH:13]=[CH:14][C:15]=1[N:16]=[N:17][C:18]1[C:23]([N+:24]([O-:26])=[O:25])=[CH:22][C:21]([N+:27]([O-:29])=[O:28])=[CH:20][C:19]=1[C:31]#[N:32])[N:8]([CH2:11][CH3:12])[CH2:9][CH3:10])(=[O:3])[CH3:2]

참가 물질

5

반응물 3

HCID 962WaterHCID 8929Sodium CyanideHCID 3017688N-(2-((2-Chloro-4,6-dinitrophenyl)azo)-5-(diethylamino)phenyl)acetamide

생성물 1

HCID 90383Acetamide, N-(2-(2-(2-cyano-4,6-dinitrophenyl)diazenyl)-5-(diethylamino)phenyl)-수율 82.5%

시약·촉매·용매 1

HCID 8151beta,beta'-Thiodipropionitrile용매

반응 조건

온도
132.5 °C

실험 절차

7.175 parts of cuprous bromide are dissolved in 350 parts of bis-(β-cyanoethyl) sulfide. 43.45 parts of 3-acetamido-4-(2'-chloro-4',6'-dinitrophenylazo)-N,N-diethylaniline are introduced, and the mass is brought to 130° C. During 1 hour 30 minutes, in an open reactor, a solution of 6.35 parts of sodium cyanide in 20 parts of water is added to the mixture and the mixture is stirred for 4 hours at 130-135° C. The product formed is separated as in Example 1; 35.12 parts of 3-acetamido-4-(2'-cyano-4', 6'-dinitrophenylazo)-N,N-diethylaniline are obtained. The yield is 82.5%.

후처리

  1. customis brought to 130° C
  2. customThe product formed
  3. customis separated as in Example 1

출처 및 근거

ORD 기록
ord-88a7ccb32fd64c279157b75a430c390b
출처 데이터셋
uspto-grants-1978_11
특허 번호
US04126610

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