Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Fosmidomycin → Fosmidomycin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Fosmidomycin | HCID 572 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Potassium Alum | HCID 24856 | — |
| 반응물 | Sodium | HCID 5360545 | — |
| 생성물 | Fosmidomycin | HCID 572 | 74% |
| 생성물 | Aluminum | HCID 5359268 | — |
반응 단계
To an aqueous solution (45 ml.) of potassium alum (9.17 g.) was added mono sodium salt of 3-(N-formyl-N-hydroxyamino)propylphosphonic acid (3.08 g.) with stirring, and the solution was adjusted to pH 6-7 with 10% aqueous sodium hydroxide solution and then stirred for 2 hours at ambient temperature. The precipitating materials were collected by filtration, washed twice with water (each 10 ml.) and dried to give aluminum salt of 3-(N-formyl-N-hydroxyamino)propylphosphonic acid (2.28 g.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04206156 |
| 출처 데이터셋 | uspto-grants-1980_06 |
| ORD ID | ord-b587d404e39a46bf913f82d39f50caeb |
| 출처 메모 | uspto-grants-1980_06 |