Potassium Carbonate → HCID 13723675, 화합물

HRID 1706691노트

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HRID 1706691 반응식
Br[CH:2]([CH2:8]Br)[C:3]([O:5][CH2:6][CH3:7])=[O:4].[CH3:10][C:11]1[CH:12]=[C:13]([OH:19])[C:14](=[CH:16][C:17]=1[CH3:18])[OH:15].C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH3:10][C:11]1[C:17]([CH3:18])=[CH:16][C:14]2[O:15][CH:2]([C:3]([O:5][CH2:6][CH3:7])=[O:4])[CH2:8][O:19][C:13]=2[CH:12]=1

참가 물질

5

반응물 3

HCID 11430Potassium CarbonateHCID 97945Ethyl 2,3-dibromopropionateHCID 127302874,5-Dimethylbenzene-1,2-diol

생성물 1

HCID 13723675HCID 13723675, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

반응 조건

온도
30 °C

실험 절차

86 g of ethyl 2,3-dibromopropionate was added, over a 15-minute period, to a stirred mixture of 41 g of 6A, 97 g of potassium carbonate and 300 ml of acetone. The temperature of the mixture rose to 60° C. The mixture was refluxed for 19 hours, cooled to 30° C. and filtered. The solvent was evaporated from the filtrate under reduced pressure. The residue was recrystallized from hexane to give 6, mp: 71°-72° C.

후처리

  1. customrose to 60° C
  2. temperatureThe mixture was refluxed for 19 hours
  3. filtrationfiltered
  4. customThe solvent was evaporated from the filtrate under reduced pressure
  5. customThe residue was recrystallized from hexane
  6. customto give 6, mp: 71°-72° C.

출처 및 근거

ORD 기록
ord-e58108ecf2e148408ec945bc59295362
출처 데이터셋
uspto-grants-1980_06
특허 번호
US04208424

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