Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Butanol → 2-(Bromomethyl)-4-(4-chloro-1-naphthalenyloxymethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Butanol | HCID 263 | — |
| 반응물 | p-Toluenesulfonic acid | HCID 6101 | — |
| 반응물 | 2-Bromo-1-(2,4-dichlorophenyl)ethan-1-one | HCID 75828 | — |
| 반응물 | 3-(4-Chloro-1-naphthalenyloxy)-1,2-propanediol | HCID 20332658 | — |
| 용매 | Benzene | HCID 241 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-(Bromomethyl)-4-(4-chloro-1-naphthalenyloxymethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane | HCID 20332695 | — |
반응 단계
A mixture of 13.6 parts of 2-bromo-1-(2,4-dichlorophenyl)-1-ethanone, 15.2 parts of 3-(4-chloro-1-naphthalenyloxy)-1,2-propanediol, 3 parts of 4-methylbenzenesulfonic acid, 80 parts of butanol and 180 parts of benzene is stirred and refluxed for 24 hours with water-separator. The reaction mixture is evaporated and the residue is triturated in 2-propanol. The product is filtered off and crystallized from butanol, yielding A+B 2-(bromomethyl)-4-(4-chloro-1-naphthalenyloxymethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane; mp. 122.7° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04209447 |
| 출처 데이터셋 | uspto-grants-1980_06 |
| ORD ID | ord-1a1aaba9300a4b73ab119fd2a5fda7eb |
| 출처 메모 | uspto-grants-1980_06 |