6-Phenyl-1,2,4-triazolo[4,3-a]pyrimidine → 6-(Phenyl)-1,2,4-triazolo[1,5-a]pyrimidine

HRID 1707047노트

반응식

HRID 1707047 반응식
[C:1]1([C:7]2[CH:8]=[N:9][C:10]3[N:11]([CH:13]=[N:14][N:15]=3)[CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>C(O)=O>[C:1]1([C:7]2[CH:8]=[N:9][C:10]3[N:15]([N:14]=[CH:13][N:11]=3)[CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

3

반응물 1

HCID 203333416-Phenyl-1,2,4-triazolo[4,3-a]pyrimidine

생성물 1

HCID 100813826-(Phenyl)-1,2,4-triazolo[1,5-a]pyrimidine

시약·촉매·용매 1

HCID 284Formic Acid용매

실험 절차

A mixture of 1.0 g. of 6-(phenyl)-1,2,4-triazolo[4,3-a]pyrimidine and 10 ml. of 97% formic acid is refluxed for 5 hours and the excess formic acid is removed under reduced pressure. The solid residue is collected, washed with hexane and recrystallized from glacial acetic acid to give the product as crystals, m.p. 164°-167° C.

후처리

  1. additionA mixture of 1.0 g
  2. customthe excess formic acid is removed under reduced pressure
  3. customThe solid residue is collected
  4. washwashed with hexane
  5. customrecrystallized from glacial acetic acid

출처 및 근거

ORD 기록
ord-b6f8ba44ce114f2c87513d73709ee6a4
출처 데이터셋
uspto-grants-1980_06
특허 번호
US04209621

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