Acetic Acid → 6-(Phenyl)-1,2,4-triazolo[1,5-a]pyrimidine

HRID 1707048노트

반응식

HRID 1707048 반응식
[C:1]1([C:7]([CH2:9]C=O)=N)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:12][C:13]1[N:17]=[CH:16][NH:15][N:14]=1.[C:18](O)(=O)C>>[C:1]1([C:7]2[CH:9]=[N:12][C:13]3[N:14]([N:15]=[CH:16][N:17]=3)[CH:18]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

4

반응물 3

HCID 176Acetic AcidHCID 86737068(Phenyl)formimidoylacetaldehydeHCID 178418311HCID 178418311, 화합물

생성물 1

HCID 100813826-(Phenyl)-1,2,4-triazolo[1,5-a]pyrimidine

실험 절차

An equimolar mixture of (phenyl)formimidoylacetaldehyde and 3-amino-1,2,4-triazole in glacial acetic acid (5 ml. acetic acid to 0.01 mole of reagents) is refluxed for 2 hours and allowed to cool to room temperature. The solid which separates is collected, washed with glacial acetic acid and dried. The solid is recrystallized from glacial acetic acid to give the product, m.p. 164°-167° C.

후처리

  1. temperatureis refluxed for 2 hours
  2. customThe solid which separates is collected
  3. washwashed with glacial acetic acid
  4. customdried
  5. customThe solid is recrystallized from glacial acetic acid
  6. customto give the product, m.p. 164°-167° C.

출처 및 근거

ORD 기록
ord-283ad2879ae04803951bae3c9283c4f9
출처 데이터셋
uspto-grants-1980_06
특허 번호
US04209621

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